The U.S. Embassy hosted the first AmCham meeting of 2006 on 21 February in its new Chancery in Yunusobod. Ambassador Purnell welcomed the members and discussed the current state of U.S.-Uzbek bilateral relations. The presentation was followed by the Ambassador's personal tour of the Information Resources Center. The guests then enjoyed appetizers and American wines at a reception in the enclosed atrium.

After 30 months of construction, the Chancery was officially dedicated in December 2005. The entire site is 4.5 hectares and cost approximately $60 million. The constriction had a very positive effect on the local economy. Approximately 300 Uzbeks worked on the site and a substantial portion of the building materials, including all of the steel and concrete, was purchased locally. It is estimated that the project added in excess of $ 10 million to the local economy. The Information Resource Center (IRC) is the Embassy's research and reference service,   primarily for students, journalists and government officials. It offers users a sophisticated collection of non-circulating books, videos and other materials on topics including U.S. politics, history, culture, and economics, as well as democracy and the environment. The IRC also has copies of leading American and Western newspapers and magazines in electronic or print formats. All services free of charge.

The Chancery houses an impressive collection of over 70 pieces of art, including several by Native American artists. There are also a few pieces by Uzbek artists Yuri Useynov. According to the State Department's curator, the collection "represents the diversity of the American landscape drawn from the historical richness of the land." The collection belongs to the State Department and is a permanent feature of the building.